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Gut Issues? What You Need to Know About Endotoxins

Written by Nick & Nathan

July 5, 2020

We have both dealt with many gut issues in our health journey and can definitely relate to the unpleasant feeling that comes with it. Whether we want to call it IBS, Crohn’s, GERD, SIBO, Candida, Ulcerative Colitis, Constipation, Hemorrhoids, Gassing, Bloating, or Diarrhea, all of these symptoms are synonymous with elevated stress hormones (cortisol, serotonin, & estrogen) and Endotoxins. Constantly having to deal with brain fog, sluggish feelings, low energy, anxiety, insomnia, and inflammation, can all stem from having a build up of endotoxins. 

Resources: Article 1, Article 2, Video #1, Video #2 (Georgi Dinkov explains in this video how endotoxin creates many other stress hormones in the body)

What is endotoxins? Scientifically known as lipopolysaccharide (LPS), is a cytotoxic and neurotoxic compound that pathogenic gram-negative bacteria release in the intestines. Endotoxin gets released when we eat poorly, indigestible food allowing for the bacteria to grow and multiply. We will list foods below that create endotoxin loads inside the intestines, but we discuss more in detail here on stress-causing nutritional habits.  If we don’t realize we have been under chronic endotoxin assault causing systemic inflammation throughout the body, we will continue chasing our symptoms. 

Foods to Avoid that Create Endotoxins

  1. Polyunsaturated Fats & Vegetable Oils (omega-3/6s, canola, sunflower, algae, DHA, soybean, corn, safflower, 
  2. Excessive nuts, seeds, legumes, beans and soy products
  3. Raw green vegetables (opt for well-cooked)
  4. Processed and IRON Fortified Foods (oatmeal, cookies, cakes, pastries, cereals, breads, pastas, protein bars, chips)

An article by New Scientist titled “Bacteria lurking in your blood could be culprit in countless diseases” focuses on endotoxin and the systemic inflammatory effect that it has, which contributes to weight gain, Alzheimer’s, Diabetes, heart Disease, Arthritis, and autoimmune diseases.  Endotoxin continues to break down our gut barrier, and starts getting into the bloodstream. It is then treated as you have a bacteria in your bloodstream and activates the TLR-4 and is the primary receptor for detecting external pathogens. Basically this is a fake alarm when it comes from endotoxin, but creates the same immune response throughout the body. When this immune response is constantly triggered day in and day out for many years, this deteriorates the metabolism and destroys the gut from being able to function properly. 


1. Eat easy-to-digest foods

In-season fruit, maple syrup, honey, grass fed milk and aged cheeses, well-cooked roots, wild-caught shellfish, pasture-raised eggs, fresh juice, butter, ghee, bone broth/gelatin, collagen, grass fed wild game/red meat,

2. Ingesting in-soluble fiber

Eat one raw organic medium-large carrot 3-5 days a week. It is not for nutrition, but allows the pulling out of endotoxin and prevents reabsorption of estrogen through the intestinal wall.

Bamboo shoots

Well-cooked White Button Mushrooms

3. Activated Charcoal 

We recommend 1-5 teaspoons daily on an empty stomach, no more than 1-2 days/week. Use on the days you don’t get a carrot salad or bamboo shoot. Animals have been shown to have a lifespan of 20-30% expansion when charcoal was added to their diet.

4. Take a systemic enzyme blend with a phthalate-free enteric coated capsule. We recommend Mitolife Dissolv-It-All (use code consciouslift at checkout to save $$), which is a powerful blend of Nattokinase, Serrapeptase, and co-factors which help them to work more efficiently. Those two proteolytic enzymes are very effective and break down excessive fibrin and scar tissue throughout the body. 

5. Just Thrive Spore-Based Probiotic (use code consciouslift to save $$). Check out the interview on Mitolife Radio where Kiran Krishnan, the microbiologist explains how the 4 “influencer” strains have been shown to reduce endotoxin by 42% in just one month. 

Download our free trigger point guide where we teach and educate more in depth on the basics of rebuilding a foundation to health, while mitigating many unknown stressors that could be present in your current lifestyle. Follow us on Instagram: Lamannafitness and Colonna_Fitness, Youtube: & Mitigate Stress 2.0 where we constantly provide more in-depth content for visual learners. 

If you have seen value in this article, schedule a FREE stress consultation on the front page of our website or donate down below. At the very least, share this article and our mission with anyone in your close circle that can benefit from becoming the best versions of themselves.

God Bless,

Nick & Nathan

Other Resources: Diabetes & Endotoxin, Asthma & Endotoxin, Epilepsy & Endotoxin, Chronic Pain & Endotoxin, Multiple Sclerosis & Endotoxin, Depression & Endotoxin, Chronic Inflammation & Endotoxin


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